What is reliability of topology?
The reliability of a topology prediction is based on the trained Hidden Markov Model of CCTOP and is
calculated by summing up the posterior probabilities
along the state path determined by the Viterbi algorithm. As it can be seen
in the plot below, the measured reliabilities in the
3D benchmark set highly correlate with the prediction accuracy
(more information can be found here, or in the descriptive articles).
Predictions are sorted according to their reliability, the topology accuracies and reliability measured on benchmark set (red and magenta, respectively) are plotted against coverage.